{"id":11139,"date":"2025-06-25T18:14:55","date_gmt":"2025-06-25T09:14:55","guid":{"rendered":"https:\/\/imprint-india.org\/column\/?p=11139"},"modified":"2025-09-01T19:49:55","modified_gmt":"2025-09-01T10:49:55","slug":"acnethole_how_to_take","status":"publish","type":"post","link":"https:\/\/nmaus.org\/column\/acne-medication\/acnethole_how_to_take\/","title":{"rendered":"\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u306e\u670d\u7528\u65b9\u6cd5\u3092\u89e3\u8aac\uff5c\u98f2\u307f\u65b9\u30fb\u30bf\u30a4\u30df\u30f3\u30b0\u30fb\u6ce8\u610f\u70b9\u307e\u3068\u3081"},"content":{"rendered":"<p><img decoding=\"async\" loading=\"lazy\" src=\"\/column\/wp-content\/uploads\/acnethole_how_to_take.webp\" alt=\"\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u306e\u670d\u7528\u65b9\u6cd5\u3092\u89e3\u8aac\uff5c\u98f2\u307f\u65b9\u30fb\u30bf\u30a4\u30df\u30f3\u30b0\u30fb\u6ce8\u610f\u70b9\u307e\u3068\u3081\" width=\"900\" height=\"450\" class=\"eyecatch aligncenter size-full wp-image-11154\" \/>\u3057\u3064\u3053\u3044\u4e2d\u7b49\u5ea6\uff5e\u91cd\u75c7\u30cb\u30ad\u30d3\u306b\u5bfe\u3057\u3066\u3001\u512a\u308c\u305f\u52b9\u679c\u3092\u767a\u63ee\u3059\u308b\u30cb\u30ad\u30d3\u6cbb\u7642\u85ac<a href=\"\/product.php?pid=3265\" data-internallinksmanager029f6b8e52c=\"313\" title=\"\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u306e\u901a\u8ca9-\u30b3\u30b3\u30ed\u85ac\u5c40\" rel=\"nofollow\">\u30a2\u30af\u30cd\u30c8\u30fc\u30eb<\/a>\u3067\u3059\u304c\u3001\u305d\u306e&ldquo;\u512a\u308c\u305f\u52b9\u679c&rdquo;\u306f<span class=\"yellow-line\">\u300c\u6b63\u3057\u3044\u670d\u7528\u65b9\u6cd5\u300d\u3092\u77e5\u3063\u3066\u3053\u305d\u5b9f\u611f\u3067\u304d\u308b\u3082\u306e<\/span>\u3067\u3059\u3002<\/p>\n<p>\u3053\u306e\u30da\u30fc\u30b8\u3067\u306f\u3001\u521d\u3081\u3066\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u3092\u4f7f\u3046\u4eba\u304c\u77e5\u3063\u3066\u304a\u304d\u305f\u3044<span class=\"bold\">\u300c\u6b63\u3057\u3044\u98f2\u307f\u65b9\u300d<\/span>\u304b\u3089<span class=\"bold\">\u300c\u3084\u3063\u3066\u306f\u3044\u3051\u306a\u3044\u843d\u3068\u3057\u7a74\u300d\u300c\u610f\u5916\u3068\u5fd8\u308c\u304c\u3061\u306a\u6ce8\u610f\u70b9\u300d<\/span>\u307e\u3067\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n<div id=\"toc_container\" class=\"no_bullets\"><p class=\"toc_title\">\u76ee\u6b21<\/p><ul class=\"toc_list\"><li><a href=\"#112\">1\u65e51\u56de\uff1f\u305d\u308c\u3068\u30822\u56de\uff1f\uff1a\u6b63\u89e3\u306f\u4f53\u91cd\u30fb\u91cd\u75c7\u5ea6\u3057\u3060\u3044\u3067\u5909\u308f\u308b<\/a><\/li><li><a href=\"#ldquordquoNG\">\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u3092\u98f2\u3080\u306e\u306f\u5fc5\u305a&ldquo;\u98df\u5f8c&rdquo;\uff1a\u7a7a\u8179\u304cNG\u306a\u7406\u7531\u3068\u306f\uff01\uff1f<\/a><\/li><li><a href=\"#i\">\u3069\u308c\u304f\u3089\u3044\u306e\u91cf\u3092\u3001\u3069\u306e\u304f\u3089\u3044\u7d9a\u3051\u308c\u3070\u3044\u3044\uff1f<\/a><\/li><li><a href=\"#i-2\">\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u3092\u3046\u3063\u304b\u308a\u98f2\u307f\u5fd8\u308c\u305f\uff01\u305d\u306e\u3068\u304d\u614c\u3066\u305a\u306b\u3059\u3079\u304d\u3053\u3068<\/a><\/li><li><a href=\"#i-3\">\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u306b\u306f\u4e00\u7dd2\u306b\u98f2\u3093\u3067\u306f\u3044\u3051\u306a\u3044\u85ac\u3084\u30b5\u30d7\u30ea\u304c\u3042\u308b<\/a><\/li><li><a href=\"#i-4\">\u305f\u3060\u98f2\u3080\u3060\u3051\u3058\u3083\u30c0\u30e1\u3002\u98f2\u307f\u65b9\u3092\u628a\u63e1\u3057\u3066\u98f2\u3080\u306e\u304c\u6210\u529f\u306e\u30ab\u30ae<\/a><\/li><\/ul><\/div>\n<h2><span id=\"112\">1\u65e51\u56de\uff1f\u305d\u308c\u3068\u30822\u56de\uff1f\uff1a\u6b63\u89e3\u306f\u4f53\u91cd\u30fb\u91cd\u75c7\u5ea6\u3057\u3060\u3044\u3067\u5909\u308f\u308b<\/span><\/h2>\n<p>\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u306e\u6709\u52b9\u6210\u5206\u30a4\u30bd\u30c8\u30ec\u30c1\u30ce\u30a4\u30f3\u306b\u3064\u3044\u3066\u3001\u300c<span class=\"bold\">\u4f53\u91cd1kg\u3042\u305f\u308a0.5\u301c1.0mg<\/span>\u30921\u65e5<span class=\"bold\">1\u56de<\/span>\u3082\u3057\u304f\u306f<span class=\"bold\">2\u56de<\/span>\u306b\u5206\u3051\u3066\u670d\u7528\u300d\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n\u3064\u307e\u308a\u3001\u300c\u4f53\u91cd\u304c60kg\u306a\u30891\u65e5\u3042\u305f\u308a<span class=\"bold\">30\uff5e60mg<\/span>\u306b\u306a\u308b\u3088\u3046\u306b\u8abf\u6574\u305b\u3088\u300d\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u304c\u3001\u30cb\u30ad\u30d3\u6cbb\u7642\u306e\u73fe\u5834\u3067\u30a4\u30bd\u30c8\u30ec\u30c1\u30ce\u30a4\u30f3\u304c\u51e6\u65b9\u3055\u308c\u308b\u5834\u5408\u3001<span class=\"yellow-line\">\u305d\u308c\u307b\u3069\u53b3\u5bc6\u306b\u8a08\u7b97\u3055\u308c\u308b\u308f\u3051\u3067\u306f\u306a\u3044<\/span>\u3088\u3046\u3067\u3059\u3002<\/p>\n<ul class=\"listbox\" style=\"margin-top:0;\">\n<li>\u4e2d\u7b49\u5ea6\u306e\u30cb\u30ad\u30d3\u306a\u3089<span class=\"bold\">\u30a4\u30bd\u30c8\u30ec\u30c1\u30ce\u30a4\u30f320mg<\/span>\u304b\u3089\u670d\u7528\u3092\u958b\u59cb<\/li>\n<li>\u4e0a\u8a18\u3067\u8db3\u308a\u306a\u3051\u308c\u3070\u4f53\u91cd\u306b\u5fdc\u3058\u3066<span class=\"bold\">1kg\u3042\u305f\u308a0.5mg\u3067\u8abf\u6574<\/span>\u3059\u308b<\/li>\n<li>\u91cd\u75c7\u30cb\u30ad\u30d3\u306a\u3089<span class=\"bold\">\u4f53\u91cd1kg\u3042\u305f\u308a\u30a4\u30bd\u30c8\u30ec\u30c1\u30ce\u30a4\u30f31.0mg<\/span>\u3067\u670d\u7528\u3059\u308b<\/li>\n<\/ul>\n<p>\u306a\u304a<span class=\"bold\">\u30011\u56de\u3067\u98f2\u3080\u304b2\u56de\u306b\u5206\u3051\u3066\u98f2\u3080\u304b<\/span>\u306e\u5224\u65ad\u306f\u3001\u670d\u7528\u91cf\u306b\u5fdc\u3058\u307e\u3059\u3002<\/p>\n<ul class=\"listbox\" style=\"margin-top:0;\">\n<li>1\u65e5\u306e\u670d\u7528\u91cf\u304c<span class=\"bold\">20mg<\/span>\u306a\u30891\u56de\u3067\u670d\u7528<\/li>\n<li>1\u65e5\u306e\u670d\u7528\u91cf\u304c<span class=\"bold\">40mg\u4ee5\u4e0a<\/span>\u306a\u30892\u56de\u306b\u5206\u3051\u3066\u670d\u7528<\/li>\n<\/ul>\n<h2><span id=\"ldquordquoNG\">\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u3092\u98f2\u3080\u306e\u306f\u5fc5\u305a&ldquo;\u98df\u5f8c&rdquo;\uff1a\u7a7a\u8179\u304cNG\u306a\u7406\u7531\u3068\u306f\uff01\uff1f<\/span><\/h2>\n<p><img decoding=\"async\" loading=\"lazy\" src=\"\/column\/wp-content\/uploads\/joi-23.webp\" alt=\"\u5973\u533b\" width=\"400\" height=\"601\" class=\"alignleft size-full wp-image-11155\" \/>\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u306b\u306f\u3001<span class=\"bold\">\u300c\u8102\u6eb6\u6027\u300d<\/span>\u3068\u3044\u3046\u6027\u8cea\u304c\u3042\u308a\u307e\u3059\u3002<br \/>\n\u3053\u308c\u306f<span class=\"yellow-line\">\u300c\u8102\u80aa\u306b\u6eb6\u3051\u3066\u5438\u53ce\u3055\u308c\u308b\u6027\u8cea\u304c\u3042\u308b\u300d<\/span>\u3068\u3044\u3046\u610f\u5473\u3067\u3042\u308a\u3001<span class=\"red\">\u80c3\u306e\u4e2d\u306b\u8102\u8cea\u304c\u306a\u3044\u7a7a\u8179\u6642\u306f\u5438\u53ce\u7387\u304c\u3088\u304f\u3042\u308a\u307e\u305b\u3093\u3002<\/span><br \/>\n\u3068\u3044\u3046\u308f\u3051\u3067\u3001<span class=\"yellow-line\">\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u306e\u52b9\u679c\u3092\u3057\u3063\u304b\u308a\u5b9f\u611f\u3059\u308b\u306b\u306f\u98df\u5f8c\u306e\u670d\u7528\u304c\u671b\u307e\u3057\u3044<\/span>\u3068\u3044\u3048\u307e\u3059\u3002<\/p>\n<p>\u5b9f\u969b\u306b\u884c\u308f\u308c\u305f\u8a66\u9a13\u3067\u3082\u3001\u4e0b\u8a18\u306e\u3088\u3046\u306a\u7d50\u679c\u304c\u51fa\u3066\u3044\u307e\u3059\u3002<\/p>\n<blockquote>\n<p>Mean plasma levels of the isotretinoin-Lidose formulation during fasting reached 66.8% of that observed with a fatty meal, and those of the isotretinoin formulation only reached 39.6% of that observed with a fatty meal.<\/p>\n<p><span class=\"bold\">\u2015\u2015\u7a7a\u8179\u6642\u306e\u30a4\u30bd\u30c8\u30ec\u30c1\u30ce\u30a4\u30f3-\u30ea\u30c9\u30fc\u30b9\u88fd\u5264\u306e\u5e73\u5747\u8840\u6f3f\u6fc3\u5ea6\u306f\u3001\u8102\u80aa\u5206\u306e\u591a\u3044\u98df\u4e8b\u6442\u53d6\u6642\u306b\u89b3\u5bdf\u3055\u308c\u308b\u6fc3\u5ea6\u306e 66.8% \u306b\u9054\u3057\u307e\u3057\u305f\u304c\u3001\u30a4\u30bd\u30c8\u30ec\u30c1\u30ce\u30a4\u30f3\u88fd\u5264\u306e\u5e73\u5747\u8840\u6f3f\u6fc3\u5ea6\u306f\u8102\u80aa\u5206\u306e\u591a\u3044\u98df\u4e8b\u6442\u53d6\u6642\u306b\u89b3\u5bdf\u3055\u308c\u308b\u6fc3\u5ea6\u306e 39.6% \u306b\u3057\u304b\u9054\u3057\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/span><\/p>\n<p>\u53c2\u8003\u5143\uff1a<a href=\"https:\/\/www.jaad.org\/article\/S0190-9622(13)00658-0\/abstract?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noopener\">Comparative pharmacokinetic profiles of a novel isotretinoin formulation (isotretinoin-Lidose) and the innovator isotretinoin formulation: A randomized, 4-treatment, crossover study<\/a>\n<\/p>\n<\/blockquote>\n<p>\u305f\u3060\u3057\u3001\u305f\u3068\u3048\u3070\u30a4\u30bd\u30c8\u30ec\u30c1\u30ce\u30a4\u30f3\u3092\u51e6\u65b9\u3057\u3066\u3044\u308b\u76ae\u819a\u79d1\u30af\u30ea\u30cb\u30c3\u30af\u3067\u300c\u9ad8\u8102\u8cea\u306e\u98df\u4e8b\u3092\u3068\u308b\u3079\u3057\u300d\u306e\u3088\u3046\u306a\u6307\u793a\u304c\u306a\u3055\u308c\u308b\u308f\u3051\u3067\u306f\u306a\u304f\u3001<span class=\"yellow-line\">\u901a\u5e38\u306e\u98df\u4e8b\u3092\u3068\u3063\u3066\u3044\u308c\u3070\u5341\u5206\u306b\u5438\u53ce\u3055\u308c\u308b<\/span>\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<br \/>\n\u305d\u3082\u305d\u3082\u8102\u8cea\u304c\u591a\u3059\u304e\u308b\u98df\u4e8b\u306f\u808c\u306b\u3082\u826f\u304f\u306a\u3044\u306e\u3067\u3001\u3042\u307e\u308a\u6c17\u306b\u3057\u904e\u304e\u305a\u3001<span class=\"bold\">\u5e38\u8b58\u306e\u7bc4\u56f2\u5185\u3067\u30e1\u30cb\u30e5\u30fc\u3092\u9078\u3073\u307e\u3057\u3087\u3046\u3002<\/span><\/p>\n<h2><span id=\"i\">\u3069\u308c\u304f\u3089\u3044\u306e\u91cf\u3092\u3001\u3069\u306e\u304f\u3089\u3044\u7d9a\u3051\u308c\u3070\u3044\u3044\uff1f<\/span><\/h2>\n<p>\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u306f\u3001\u6bce\u65e5\u9069\u5207\u306a\u91cf\u306e\u670d\u7528\u3092\u7d9a\u3051\u3001<span class=\"yellow-line\">\u670d\u7528\u3057\u305f\u6709\u52b9\u6210\u5206\u306e\u7dcf\u91cf\u304c\u4e00\u5b9a\u306e\u6570\u5024\u306b\u9054\u3059\u308b\u3053\u3068\u304c\u6cbb\u7642\u306e\u30b4\u30fc\u30eb<\/span>\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n\u7dcf\u91cf\u306e\u76ee\u5b89\u3068\u306a\u308b\u306e\u304c\u3001<span class=\"yellow-line\">\u4f53\u91cd1kg\u5f53\u305f\u308a120\uff5e150mg<\/span>\u3067\u3059\u3002<br \/>\n\u3053\u308c\u307e\u3067\u306b\u670d\u7528\u3057\u3066\u304d\u305f\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\uff08\u30a4\u30bd\u30c8\u30ec\u30c1\u30ce\u30a4\u30f3\uff09\u306e\u7dcf\u91cf\u304c\u6240\u5b9a\u306e\u6570\u5024\u306b\u9054\u3057\u305f\u9803\u306b\u306f\u3001\u3057\u3063\u304b\u308a\u3068\u3057\u305f\u52b9\u679c\u304c\u3042\u3089\u308f\u308c\u3066\u3044\u308b\u306f\u305a\u3067\u3059\u3002<\/p>\n<p class=\"margin-bottom:10px;\">\u670d\u7528\u91cf\u3068\u6cbb\u7642\u671f\u9593\u306e\u76ee\u5b89\uff08\u4e2d\u7b49\u5ea6\u306e\u4f8b\uff09<\/p>\n<div class=\"scroll_table\" style=\"margin-bottom:20px;\">\n<table class=\"bgcolor2\" style=\"margin-bottom:0!important;width:800px;\">\n<tr>\n<th style=\"width:100px;\">\u4f53\u91cd<\/th>\n<th style=\"width:233px;\">1\u65e5\u3042\u305f\u308a\u306e\u76ee\u5b89\u91cf<br \/>\uff080.5mg\/kg\uff09<\/th>\n<th style=\"width:233px;\">\u7d2f\u7a4d\u6295\u4e0e\u91cf\uff08\u7dcf\u91cf\uff09\u306e\u76ee\u5b89<br \/>\uff08120\uff5e150mg\/kg\uff09<\/th>\n<th style=\"width:233px;\">\u6cbb\u7642\u671f\u9593\u306e\u76ee\u5b89<\/td>\n<\/tr>\n<tr>\n<th>50kg<\/th>\n<td>20mg<\/td>\n<td>2,400\uff5e3,000mg<\/td>\n<td>120\u301c150\u65e5<br \/>\uff08\u7d044\uff5e5\u30f6\u6708\uff09<\/td>\n<\/tr>\n<tr>\n<th>60kg<\/th>\n<td>30mg<\/td>\n<td>3,600\uff5e4,500mg<\/td>\n<td>120\u301c150\u65e5<br \/>\uff08\u7d044\uff5e5\u30f6\u6708\uff09<\/td>\n<\/tr>\n<tr>\n<th>70kg<\/th>\n<td>30mg<\/td>\n<td>3,600\uff5e4,500mg<\/td>\n<td>120\u301c150\u65e5<br \/>\uff08\u7d044\uff5e5\u30f6\u6708\uff09<\/td>\n<\/tr>\n<\/table>\n<\/div>\n<h2><span id=\"i-2\">\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u3092\u3046\u3063\u304b\u308a\u98f2\u307f\u5fd8\u308c\u305f\uff01\u305d\u306e\u3068\u304d\u614c\u3066\u305a\u306b\u3059\u3079\u304d\u3053\u3068<\/span><\/h2>\n<p>\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u306f\u6bce\u65e5\u670d\u7528\u3059\u3079\u304d\u533b\u85ac\u54c1\u3067\u3059\u304c\u3001\u3046\u3063\u304b\u308a\u5fd8\u308c\u3066\u3057\u307e\u3046\u3053\u3068\u3082\u3042\u308b\u3067\u3057\u3087\u3046&hellip;&hellip;\u3002<br \/>\n\u305d\u3093\u306a\u3068\u304d\u306b<span class=\"bold\">\u7d76\u5bfeNG<\/span>\u306a\u306e\u304c\u3001<span class=\"red\">2\u56de\u5206\u3092\u4e00\u5ea6\u306b\u98f2\u3080\u3053\u3068<\/span>\u3067\u3059\u3002<br \/>\n<span class=\"red\">\u526f\u4f5c\u7528\u306e\u30ea\u30b9\u30af<\/span>\u304c\u9ad8\u307e\u308a\u3001\u809d\u81d3\u3084\u808c\u306b\u8ca0\u62c5\u304c\u304b\u304b\u308b\u6050\u308c\u304c\u3042\u308b\u305f\u3081\u3067\u3059\u3002<\/p>\n<p>\u3082\u3057\u98f2\u307f\u5fd8\u308c\u306b\u6c17\u3065\u3044\u305f\u3089\u3001\u6b21\u306e\u5bfe\u5fdc\u3092\u53c2\u8003\u306b\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<ul class=\"listbox\" style=\"margin-top:0;\">\n<li>\u6c17\u3065\u3044\u305f\u6642\u70b9\u3067<span class=\"bold\">1\u56de\u5206\u3060\u3051<\/span>\u670d\u7528<\/li>\n<li><span class=\"bold\">\u6b21\u306e\u670d\u7528\u6642\u9593\u304c\u8fd1\u3044<\/span>\u5834\u5408\u306f\u3001\u98f2\u307f\u5fd8\u308c\u5206\u3092\u30b9\u30ad\u30c3\u30d7<\/li>\n<\/ul>\n<h2><span id=\"i-3\">\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u306b\u306f\u4e00\u7dd2\u306b\u98f2\u3093\u3067\u306f\u3044\u3051\u306a\u3044\u85ac\u3084\u30b5\u30d7\u30ea\u304c\u3042\u308b<\/span><\/h2>\n<p>\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u306f\u3001<span class=\"red\">\u4ed6\u306e\u85ac\u3084\u30b5\u30d7\u30ea\u3068\u306e\u7d44\u307f\u5408\u308f\u305b\u306b\u3088\u3063\u3066\u91cd\u5927\u306a\u526f\u4f5c\u7528\u304c\u51fa\u308b<\/span>\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<div class=\"midashi_ari\">\n<p>\u30dd\u30a4\u30f3\u30c8<\/p>\n<ul>\n<li><i class=\"fa fa-square\" aria-hidden=\"true\"><\/i><span class=\"bold\">\u300c\u4f75\u7528\u7981\u5fcc\u300d<\/span>\u306b\u5f53\u305f\u308b\u3082\u306e\u3068\u306e\u4f75\u7528\u306f<span class=\"red\">\u7d76\u5bfe\u306b\u907f\u3051\u308b<\/span><\/li>\n<li><i class=\"fa fa-square\" aria-hidden=\"true\"><\/i><span class=\"bold\">\u300c\u4f75\u7528\u6ce8\u610f\u300d<\/span>\u306b\u5f53\u305f\u308b\u3082\u306e\u306f\u3067\u304d\u308b\u3060\u3051\u907f\u3051\u3001<span class=\"yellow-line\">\u5fc5\u8981\u306a\u3089\u533b\u5e2b\u306b\u76f8\u8ac7\u3059\u308b<\/li>\n<\/ul>\n<\/div>\n<h3>\u7d76\u5bfe\u306b\u4f75\u7528\u3057\u3066\u306f\u3044\u3051\u306a\u3044\u4f75\u7528\u7981\u5fcc\uff01<\/h3>\n<article class=\"important_point\">\n<h4>\u30d3\u30bf\u30df\u30f3A\u30b5\u30d7\u30ea<\/h4>\n<p>\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u3068\u30d3\u30bf\u30df\u30f3A\u3092\u4e00\u7dd2\u306b\u670d\u7528\u3057\u3066\u3057\u307e\u3046\u3068\u3001<span class=\"red\">\u30d3\u30bf\u30df\u30f3A\u4e2d\u6bd2<\/span>\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<br \/>\n\u30d3\u30bf\u30df\u30f3A\u4e2d\u6bd2\u306f\u591a\u304f\u306e\u5834\u5408\u3001\u982d\u75db\u3084\u767a\u75b9\u306e\u75c7\u72b6\u304c\u307f\u3089\u308c\u308b\u4ed6\u3001\u90e8\u5206\u7684\u306a\u8131\u6bdb\u3084\u5507\u306e\u3072\u3073\u5272\u308c\u304c\u8d77\u3053\u3063\u305f\u308a\u3001\u9aa8\u6298\u3057\u3084\u3059\u304f\u306a\u3063\u305f\u308a\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\n<\/p>\n<\/article>\n<article class=\"important_point\">\n<h4>\u30c6\u30c8\u30e9\u30b5\u30a4\u30af\u30ea\u30f3\u7cfb\u6297\u751f\u7269\u8cea\uff08\u30df\u30ce\u30b5\u30a4\u30af\u30ea\u30f3\u3001\u30c9\u30ad\u30b7\u30b5\u30a4\u30af\u30ea\u30f3\u7b49\uff09<\/h4>\n<p><span class=\"red\">\u982d\u84cb\u5185\u5727\u4ea2\u9032<\/span>\u306e\u30ea\u30b9\u30af\u304c\u3042\u308a\u307e\u3059\u3002<br \/>\n\u982d\u84cb\u5185\u5727\u304c\u9ad8\u307e\u308b\u3053\u3068\u3067\u3001\u6fc0\u3057\u3044\u982d\u75db\u3084\u8996\u899a\u7570\u5e38\u3001\u5410\u304d\u6c17\u3084\u5614\u5410\u306a\u3069\u306e\u75c7\u72b6\u304c\u3042\u3089\u308f\u308c\u307e\u3059\u3002<\/p>\n<\/article>\n<h3>\u4e00\u7dd2\u306b\u670d\u7528\u3059\u308b\u6642\u306b\u6ce8\u610f\u3057\u306a\u3051\u308c\u3070\u3044\u3051\u306a\u3044\u4f75\u7528\u6ce8\u610f<\/h3>\n<article class=\"important_point\">\n<h4>\u30a2\u30eb\u30b3\u30fc\u30eb<\/h4>\n<p>\u98f2\u9152\u306f<span class=\"red\">\u809d\u6a5f\u80fd\u969c\u5bb3\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u3066\u3057\u307e\u3046<\/span>\u305f\u3081\u3001\u670d\u7528\u4e2d\u306f\u57fa\u672c\u7684\u306b<span class=\"bold\">\u7981\u9152<\/span>\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<\/article>\n<article class=\"important_point\">\n<h4>\u30d5\u30a7\u30cb\u30c8\u30a4\u30f3\u306a\u3069\u306e\u6297\u3066\u3093\u304b\u3093\u85ac<\/h4>\n<p>\u30d3\u30bf\u30df\u30f3A\u306e\u4ee3\u8b1d\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u3067\u3001<span class=\"red\">\u9aa8\u7c97\u9b06\u75c7\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u3066\u3057\u307e\u3046<\/span>\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<\/article>\n<h2><span id=\"i-4\">\u305f\u3060\u98f2\u3080\u3060\u3051\u3058\u3083\u30c0\u30e1\u3002\u98f2\u307f\u65b9\u3092\u628a\u63e1\u3057\u3066\u98f2\u3080\u306e\u304c\u6210\u529f\u306e\u30ab\u30ae<\/span><\/h2>\n<p>\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u306e\u52b9\u679c\u3092\u6700\u5927\u9650\u306b\u5f15\u304d\u51fa\u3059\u306b\u306f\u3001\u4ee5\u4e0b\u306e\u30dd\u30a4\u30f3\u30c8\u304c\u6b20\u304b\u305b\u307e\u305b\u3093\u3002<\/p>\n<dl class=\"point_kaisetsu\">\n<dt>\u5fc5\u305a\u201c\u8102\u8cea\u3092\u542b\u3080\u98df\u5f8c\u201d\u306b\u98f2\u3080<\/dt>\n<dd>\u7a7a\u8179\u3067\u98f2\u3080\u3068\u52b9\u679c\u304c\u534a\u6e1b\u3002<span class=\"red\">\u5438\u53ce\u7387\u304c2\u500d\u4ee5\u4e0a\u5909\u308f\u308b<\/span>\u3053\u3068\u3082\u3002<\/dd>\n<dt>\u670d\u7528\u671f\u9593\u306f\u7d2f\u7a4d\u6295\u4e0e\u91cf\u304b\u3089\u9006\u7b97\u3059\u308b<\/dt>\n<dd><span class=\"yellow-line\">\u7d2f\u7a4d\u6295\u4e0e\u91cf<\/span>\u3092\u76ee\u6a19\u306b\u3057\u3066\u7d99\u7d9a\u3057\u307e\u3057\u3087\u3046\uff01<\/dd>\n<dt>\u4ed6\u306e\u85ac\u30fb\u30b5\u30d7\u30ea\u3068\u306e\u4f75\u7528\u306f\u5fc5\u305a\u78ba\u8a8d<\/dt>\n<dd><span class=\"red\">\u30d3\u30bf\u30df\u30f3A<\/span>\u3084<span class=\"red\">\u4e00\u90e8\u306e\u6297\u751f\u7269\u8cea<\/span>\u306f\u5371\u967a\u3002\u81ea\u5df1\u5224\u65ad\u305b\u305a\u533b\u5e2b\u304b\u85ac\u5264\u5e2b\u306b\u76f8\u8ac7\u3092\uff01<\/dd>\n<\/dl>\n<p>\u3053\u306e3\u3064\u3060\u3051\u62bc\u3055\u3048\u3066\u304a\u3051\u3070\u3001<span class=\"yellow-line\">\u521d\u3081\u3066\u3067\u3082\u5b89\u5fc3\u3057\u3066\u30b9\u30bf\u30fc\u30c8\u3067\u304d\u307e\u3059\u3002<\/span><br \/>\n\u3057\u3063\u304b\u308a\u62bc\u3055\u3048\u305f\u3046\u3048\u3067\u3001\u9069\u5207\u306a\u7528\u6cd5\u7528\u91cf\u3092\u628a\u63e1\u3057\u3066\u4f7f\u3044\u59cb\u3081\u3066\u307f\u307e\u3057\u3087\u3046\uff01<\/p>\n<div class=\"cv_button_area\">\n<figure><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-full wp-image-64\" src=\"\/products_img\/Acnethole_1.webp\" alt=\"\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\" width=\"300\" height=\"250\" \/><\/figure>\n<div class=\"cv_button_area_inner\">\n<p class=\"btn\"><a href=\"\/product.php?pid=3265\"><span class=\"product_except\">\u30a2\u30af\u30cd\u30c8\u30fc\u30eb<\/span>\u306e\u901a\u8ca9\u30da\u30fc\u30b8\u3092\u898b\u308b<\/a><\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u3057\u3064\u3053\u3044\u4e2d\u7b49\u5ea6\uff5e\u91cd\u75c7\u30cb\u30ad\u30d3\u306b\u5bfe\u3057\u3066\u3001\u512a\u308c\u305f\u52b9\u679c\u3092\u767a\u63ee\u3059\u308b\u30cb\u30ad\u30d3\u6cbb\u7642\u85ac\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u3067\u3059\u304c\u3001\u305d\u306e&ldquo;\u512a\u308c\u305f\u52b9\u679c&rdquo;\u306f\u300c\u6b63\u3057\u3044\u670d\u7528\u65b9\u6cd5\u300d\u3092\u77e5\u3063\u3066\u3053\u305d\u5b9f\u611f\u3067\u304d\u308b\u3082\u306e\u3067\u3059\u3002 \u3053\u306e\u30da\u30fc\u30b8\u3067\u306f\u3001\u521d\u3081\u3066\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u3092\u2026<\/p>\n","protected":false},"author":1,"featured_media":11154,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":""},"categories":[409],"tags":[408,101],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.10 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u306e\u670d\u7528\u65b9\u6cd5\u3092\u89e3\u8aac\uff5c\u98f2\u307f\u65b9\u30fb\u30bf\u30a4\u30df\u30f3\u30b0\u30fb\u6ce8\u610f\u70b9\u307e\u3068\u3081 - \u30b3\u30b3\u30ed\u85ac\u5c40\u30b3\u30e9\u30e0<\/title>\n<meta name=\"description\" content=\"\u3053\u306e\u8a18\u4e8b\u3067\u306f\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u306e\u670d\u7528\u65b9\u6cd5\u306b\u3064\u3044\u3066\u89e3\u8aac\u3057\u307e\u3059\u3002\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u306f\u975e\u5e38\u306b\u52b9\u679c\u306e\u9ad8\u3044\u30cb\u30ad\u30d3\u6cbb\u7642\u85ac\u3068\u3057\u3066\u591a\u304f\u306e\u65b9\u306b\u4f7f\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u305d\u306e\u52b9\u679c\u3092\u5f97\u308b\u305f\u3081\u306b\u306f\u6b63\u3057\u3044\u670d\u7528\u65b9\u6cd5\u304c\u5fc5\u9808\u3067\u3059\uff01\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nmaus.org\/column\/acne-medication\/acnethole_how_to_take\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u306e\u670d\u7528\u65b9\u6cd5\u3092\u89e3\u8aac\uff5c\u98f2\u307f\u65b9\u30fb\u30bf\u30a4\u30df\u30f3\u30b0\u30fb\u6ce8\u610f\u70b9\u307e\u3068\u3081 - \u30b3\u30b3\u30ed\u85ac\u5c40\u30b3\u30e9\u30e0\" \/>\n<meta property=\"og:description\" content=\"\u3053\u306e\u8a18\u4e8b\u3067\u306f\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u306e\u670d\u7528\u65b9\u6cd5\u306b\u3064\u3044\u3066\u89e3\u8aac\u3057\u307e\u3059\u3002\u30a2\u30af\u30cd\u30c8\u30fc\u30eb\u306f\u975e\u5e38\u306b\u52b9\u679c\u306e\u9ad8\u3044\u30cb\u30ad\u30d3\u6cbb\u7642\u85ac\u3068\u3057\u3066\u591a\u304f\u306e\u65b9\u306b\u4f7f\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u305d\u306e\u52b9\u679c\u3092\u5f97\u308b\u305f\u3081\u306b\u306f\u6b63\u3057\u3044\u670d\u7528\u65b9\u6cd5\u304c\u5fc5\u9808\u3067\u3059\uff01\" \/>\n<meta property=\"og:url\" content=\"https:\/\/nmaus.org\/column\/acne-medication\/acnethole_how_to_take\/\" \/>\n<meta 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