{"id":10823,"date":"2025-06-18T17:35:39","date_gmt":"2025-06-18T08:35:39","guid":{"rendered":"https:\/\/imprint-india.org\/column\/?p=10823"},"modified":"2025-09-01T19:49:47","modified_gmt":"2025-09-01T10:49:47","slug":"avanight_effect","status":"publish","type":"post","link":"https:\/\/nmaus.org\/column\/ed_drug\/avanight_effect\/","title":{"rendered":"\u300cED\u6cbb\u7642\uff1d\u30d0\u30a4\u30a2\u30b0\u30e9\u300d\u3060\u3051\u3058\u3083\u306a\u3044\uff1f\u6c17\u306b\u306a\u308b\u30a2\u30d0\u30ca\u30a4\u30c8\u306e\u52b9\u679c\u306f\uff1f"},"content":{"rendered":"<p><img decoding=\"async\" loading=\"lazy\" src=\"\/column\/wp-content\/uploads\/avanight_effect.webp\" alt=\"\u300cED\u6cbb\u7642\uff1d\u30d0\u30a4\u30a2\u30b0\u30e9\u300d\u3060\u3051\u3058\u3083\u306a\u3044\uff1f\u6c17\u306b\u306a\u308b\u30a2\u30d0\u30ca\u30a4\u30c8\u306e\u52b9\u679c\u306f\uff1f\" width=\"900\" height=\"450\" class=\"eyecatch aligncenter size-full wp-image-10849\" \/>\u300cED\u306b\u805e\u304f\u85ac\u300d\u3068\u805e\u3044\u3066\u591a\u304f\u306e\u4eba\u304c\u30a4\u30e1\u30fc\u30b8\u3059\u308b\u306e\u306f<span class=\"bold\">\u300c\u30d0\u30a4\u30a2\u30b0\u30e9\u300d<\/span>\u3067\u3057\u3087\u3046\u3002<br \/>\n\u3067\u3082\u73fe\u5728\u3001\u30d0\u30a4\u30a2\u30b0\u30e9\u3068\u540c\u69d8\u306e\u52b9\u679c\u3092\u6301\u3061\u3064\u3064\u3001<span class=\"bold\">\u5373\u52b9\u6027<\/span>\u3084<span class=\"bold\">\u6301\u7d9a\u6027<\/span>\u306b\u512a\u308c\u305f\u65b0\u3057\u3044\u85ac\u304c\u7d9a\u3005\u3068\u767b\u5834\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u3053\u3067\u53d6\u308a\u4e0a\u3052\u308b<span class=\"bold\">\u300c<a href=\"\/product.php?pid=3258\" data-internallinksmanager029f6b8e52c=\"306\" title=\"\u30a2\u30d0\u30ca\u30a4\u30c8\u306e\u901a\u8ca9-\u30b3\u30b3\u30ed\u85ac\u5c40\" rel=\"nofollow\">\u30a2\u30d0\u30ca\u30a4\u30c8<\/a>\u300d<\/span>\u3082\u305d\u306e\u3072\u3068\u3064\u3067\u3059\u3002<\/p>\n<p>\u3053\u306e\u8a18\u4e8b\u3067\u306f\u3001<span class=\"yellow-line\">\u30a2\u30d0\u30ca\u30a4\u30c8\u306e\u57fa\u672c\u7684\u306a\u52b9\u679c<\/span>\u3084\u3001<span class=\"yellow-line\">\u30d0\u30a4\u30a2\u30b0\u30e9\u3068\u6bd4\u8f03\u3057\u305f\u3068\u304d\u306e\u7279\u5fb4<\/span>\u306a\u3069\u3092\u307e\u3068\u3081\u3066\u307f\u307e\u3057\u305f\u3002<\/p>\n<div id=\"toc_container\" class=\"no_bullets\"><p class=\"toc_title\">\u76ee\u6b21<\/p><ul class=\"toc_list\"><li><a href=\"#ED\">\u30a2\u30d0\u30ca\u30a4\u30c8\u306eED\u6539\u5584\u52b9\u679c\u306b\u304a\u3051\u308b\u4f5c\u7528\u306e\u4ed5\u7d44\u307f\u306f\uff1f<\/a><\/li><li><a href=\"#15\">\u30a2\u30d0\u30ca\u30a4\u30c8\u306f\u9ad8\u3044\u5373\u52b9\u6027\u306b\u3082\u671f\u5f85\u3067\u304d\u308b\uff01\uff1f\u6700\u901f15\u5206\u3067\u6027\u884c\u70ba\u304c\u53ef\u80fd\u306b\uff01\uff1f<\/a><\/li><li><a href=\"#_ldquordquo\">\u3069\u3093\u306a\u4eba\u306b\u5411\u3044\u3066\u3044\u308b\uff1f \u30a2\u30d0\u30ca\u30a4\u30c8\u306e&ldquo;\u9069\u6027\u8a3a\u65ad&rdquo;<\/a><\/li><li><a href=\"#i\">\u52c3\u8d77\u306e\u30ab\u30ae\u3068\u306a\u308b\u306e\u306f\u6027\u7684\u8208\u596e\u3084\u523a\u6fc0<\/a><\/li><li><a href=\"#ED-2\">\u30a2\u30d0\u30ca\u30a4\u30c8\u306f\u5373\u52b9\u6027\u306e\u9ad8\u3044\u65b0\u4e16\u4ee3\u306eED\u6cbb\u7642\u85ac<\/a><\/li><\/ul><\/div>\n<h2><span id=\"ED\">\u30a2\u30d0\u30ca\u30a4\u30c8\u306eED\u6539\u5584\u52b9\u679c\u306b\u304a\u3051\u308b\u4f5c\u7528\u306e\u4ed5\u7d44\u307f\u306f\uff1f<\/span><\/h2>\n<p>\u30a2\u30d0\u30ca\u30a4\u30c8\u306f\u3001\u300cPDE-5\u963b\u5bb3\u85ac\u300d\u306b\u5206\u985e\u3055\u308c\u308b<span class=\"bold\">\u30a2\u30d0\u30ca\u30d5\u30a3\u30eb<\/span>\u3092\u6709\u52b9\u6210\u5206\u3068\u3059\u308b\u533b\u85ac\u54c1\u3067\u3059\u3002<br \/>\n\u3054\u304f\u7c21\u5358\u306b\u3044\u3048\u3070\u3001<span class=\"red\">ED\u3092\u5f15\u304d\u8d77\u3053\u3059\u76f4\u63a5\u539f\u56e0<\/span>\u3068\u306a\u308b\u9175\u7d20<span class=\"red\">PDE-5\uff08\u30db\u30b9\u30db\u30b8\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc5\uff09\u306e\u50cd\u304d\u3092\u963b\u5bb3<\/span>\u3059\u308b\u3053\u3068\u3067\u3001ED\u306b\u60a9\u307e\u3055\u308c\u305a\u306b\u52c3\u8d77\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308b\u3068\u3044\u3046\u85ac\u3067\u3059\u3002<\/p>\n<p>\u305d\u3082\u305d\u3082\u52c3\u8d77\u3068\u3044\u3046\u73fe\u8c61\u306f\u3001\u6b21\u306e\u3088\u3046\u306a\u6d41\u308c\u3067\u8d77\u3053\u308a\u307e\u3059\u3002<\/p>\n<ol class=\"number_box2\">\n<li>\u6027\u7684\u306a\u523a\u6fc0\u30fb\u8208\u596e\u304c\u3042\u308b<\/li>\n<li>\u5e73\u6ed1\u7b4b\u3092\u5f1b\u7de9\u3055\u305b\u3066\u8840\u7ba1\u3092\u62e1\u5f35\u3055\u305b\u308bcGMP\uff08\u74b0\u72b6\u30b0\u30a2\u30ce\u30b7\u30f3\u4e00\u30ea\u30f3\u9178\uff09\u304c\u5897\u52a0<\/li>\n<li>\u8840\u7ba1\u62e1\u5f35\u306b\u3088\u3063\u3066\u30da\u30cb\u30b9\u306e\u6d77\u7dbf\u4f53\u306b\u8840\u6d41\u304c\u5897\u3048\u3066\u30b5\u30a4\u30ba\u304c\u5927\u304d\u304f\u306a\u308b<\/li>\n<li>\u5c04\u7cbe\u5f8c\u306bcGMP\u3092\u5206\u89e3\u3059\u308bPDE-5\u304c\u50cd\u3044\u3066\u8840\u7ba1\u304c\u53ce\u7e2e&rarr;\u30da\u30cb\u30b9\u30b5\u30a4\u30ba\u304c\u5143\u306b\u623b\u308b<\/li>\n<\/ol>\n<p>\u3064\u307e\u308a\u672c\u6765\u3001PDE-5\u306f\u52c3\u8d77\u3092\u53ce\u675f\u3055\u305b\u308b\u305f\u3081\u306b\u5fc5\u8981\u306a\u9175\u7d20\u3067\u3059\u3002<br \/>\n\u3057\u304b\u3057\u3001<span class=\"red\">ED\u3092\u767a\u75c7\u3059\u308b\u3068\u52c3\u8d77\u3067\u304d\u306a\u304f\u306a\u308b\u539f\u56e0\u3068\u306a\u3063\u3066\u3057\u307e\u3044\u307e\u3059\u3002<\/span><br \/>\n\u30b9\u30c8\u30ec\u30b9\u3084\u8001\u5316\u306a\u3069\u3001\u3055\u307e\u3056\u307e\u306a\u7406\u7531\u3067\u8208\u596e\u3057\u3066\u3082cGMP\u306e\u5206\u6ccc\u91cf\u304c\u601d\u3063\u305f\u307b\u3069\u5897\u3048\u306a\u304f\u306a\u308a\u3001<span class=\"red\">\u5e38\u306bPDE-5\u304c\u512a\u4f4d\u306a\u72b6\u614b\u306b\u306a\u308b<\/span>\u305f\u3081\u3001\u300c\u305d\u3082\u305d\u3082\u52c3\u8d77\u3067\u304d\u306a\u3044\u300d\u300c\u52c3\u8d77\u3092\u7dad\u6301\u3067\u304d\u306a\u3044\u300d\u3068\u3044\u3046\u3053\u3068\u306b&hellip;&hellip;\u3002<\/p>\n<p>\u305d\u3053\u3067\u52b9\u679c\u3092\u767a\u63ee\u3059\u308b\u306e\u304c\u3001PDE-5\u963b\u5bb3\u85ac\u306e\u30a2\u30d0\u30ca\u30d5\u30a3\u30eb\u3067\u3059\u3002<br \/>\nPDE-5\u306e\u50cd\u304d\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u3067\u3001cGMP\u304c\u30b9\u30e0\u30fc\u30ba\u306b\u4f5c\u7528\u3059\u308b\u3053\u3068\u3092\u4fc3\u3057\u3001<span class=\"yellow-line\">\u3010\u8840\u7ba1\u62e1\u5f35&rarr;\u8840\u6d41\u5897\u52a0&rarr;\u30da\u30cb\u30b9\u81a8\u5f35&rarr;\u52c3\u8d77\u3011\u3092\u30b5\u30dd\u30fc\u30c8<\/span>\u3057\u307e\u3059\u3002<\/p>\n<h2><span id=\"15\">\u30a2\u30d0\u30ca\u30a4\u30c8\u306f\u9ad8\u3044\u5373\u52b9\u6027\u306b\u3082\u671f\u5f85\u3067\u304d\u308b\uff01\uff1f\u6700\u901f15\u5206\u3067\u6027\u884c\u70ba\u304c\u53ef\u80fd\u306b\uff01\uff1f<\/span><\/h2>\n<p>\u30a2\u30d0\u30ca\u30a4\u30c8\u3082\u3001\u30d0\u30a4\u30a2\u30b0\u30e9\u3082\u3001\u300cPDE-5\u3092\u963b\u5bb3\u300d\u3068\u3044\u3046\u57fa\u672c\u7684\u306a\u52b9\u679c\u306e\u4ed5\u7d44\u307f\u306f\u5171\u901a\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n\u3057\u304b\u3057\u3001\u30a2\u30d0\u30ca\u30a4\u30c8\u306f<span class=\"yellow-line\">\u300c\u5373\u52b9\u6027\u300d\u3068\u3044\u3046\u9762\u3067\u30d0\u30a4\u30a2\u30b0\u30e9\u3088\u308a\u3082\u512a\u308c\u3066\u3044\u308b<\/span>\u3068\u3044\u3048\u307e\u3059\u3002<\/p>\n<p>\u30a2\u30d0\u30ca\u30a4\u30c8\u306e\u5148\u767a\u85ac\u3067\u3042\u308b\u30b9\u30c6\u30f3\u30c9\u30e9\u3092\u7528\u3044\u305f\u81e8\u5e8a\u8a66\u9a13\u3067\u306f\u3001\u670d\u7528\u304b\u3089<span class=\"bold\">15\u5206\u5f8c<\/span>\u306b\u6027\u884c\u70ba\u53ef\u80fd\u306a\u52c3\u8d77\u72b6\u614b\u306b\u81f3\u3063\u305f\u4eba\u306e\u5272\u5408\u306f<span class=\"yellow-line\">100mg\u306725.9%<\/span>\u3001<span class=\"yellow-line\">200mg\u306729.1%<\/span>\u3068\u3044\u3046\u7d50\u679c\u304c\u51fa\u3066\u3044\u307e\u3059\u3002<\/p>\n<table class=\"bgcolor2\" style=\"max-width:400px;width:100%;\">\n<tr>\n<th><\/th>\n<th>\u30b9\u30c6\u30f3\u30c9\u30e9<br \/>100 mg<\/th>\n<th>\u30b9\u30c6\u30f3\u30c9\u30e9<br \/>200 mg<\/th>\n<\/tr>\n<tr>\n<th>\u5e73\u5747\u5024<\/th>\n<td>25.9%<\/td>\n<td>29.1%<\/td>\n<\/tr>\n<tr>\n<th>\u4e2d\u592e\u5024<\/th>\n<td>11.1%<\/td>\n<td>13.3%<\/td>\n<\/tr>\n<\/table>\n<blockquote>\n<p>\n\u53c2\u8003\u5143\uff1a<a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=fa7d93e3-b69b-4e02-8146-89760cd8e9d6\" target=\"_blank\" rel=\"noopener\">Label: STENDRA- avanafil tablet\uff5cTable 10: Percentage of All Attempts Resulting in an Erection Sufficient for Penetration at Approximately 15 minutes After Dosing Followed by Successful Intercourse (SEP3) During the 8-Week Treatment Period in the Time to Onset of Effect (Study 4)<\/a>\n<\/p>\n<\/blockquote>\n<p>\u30d0\u30a4\u30a2\u30b0\u30e9\u306e\u5834\u5408\u3001<span class=\"red\">\u52b9\u679c\u304c\u51fa\u308b\u307e\u3067\u306b\u6700\u77ed\u3067\u308230\u5206\u4ee5\u4e0a\u306f\u304b\u304b\u308b<\/span>\u3053\u3068\u3092\u8003\u3048\u308b\u3068\u3001<span class=\"yellow-line\">\u30b9\u30c6\u30f3\u30c9\u30e9\u3084\u30a2\u30d0\u30ca\u30a4\u30c8\u306f\u5373\u52b9\u6027\u306b\u512a\u308c\u3066\u3044\u308b\u3068\u3044\u3048\u308b<\/span>\u308f\u3051\u3067\u3059\u3002<\/p>\n<p>\u3061\u306a\u307f\u306b\u3001\u30a2\u30d0\u30ca\u30a4\u30c8\u306e\u52b9\u679c\u306f\u670d\u7528\u5f8c\u30b9\u30d4\u30fc\u30c7\u30a3\u306b\u3042\u3089\u308f\u308c\u3001<span class=\"bold\">6\u6642\u9593<\/span>\u307b\u3069\u6301\u7d9a\u3057\u307e\u3059\u3002<br \/>\n\u30d0\u30a4\u30a2\u30b0\u30e9\u306e\u52b9\u679c\u6301\u7d9a\u6642\u9593\u304c4\uff5e5\u6642\u9593\u3067\u3042\u308b\u3053\u3068\u3092\u8003\u3048\u308b\u3068\u3001<span class=\"yellow-line\">\u300c\u30a2\u30d0\u30ca\u30a4\u30c8\u306f\u6301\u7d9a\u6027\u3082\u3084\u3084\u9ad8\u3044\u300d<\/span>\u3068\u3044\u3048\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n<h2><span id=\"_ldquordquo\">\u3069\u3093\u306a\u4eba\u306b\u5411\u3044\u3066\u3044\u308b\uff1f \u30a2\u30d0\u30ca\u30a4\u30c8\u306e&ldquo;\u9069\u6027\u8a3a\u65ad&rdquo;<\/span><\/h2>\n<p>\u3053\u3093\u306a\u4eba\u306b\u3001\u30a2\u30d0\u30ca\u30a4\u30c8\u306f\u5411\u3044\u3066\u3044\u307e\u3059\u3002<\/p>\n<ul class=\"listbox\" style=\"margin-top:0;\">\n<li><span class=\"bold\">\u98f2\u3093\u3067\u3059\u3050\u52b9\u679c\u3092\u5b9f\u611f\u3057\u305f\u3044<\/span><\/li>\n<li><span class=\"bold\">\u98df\u4e8b\u3092\u6c17\u306b\u305b\u305a\u98f2\u307f\u305f\u3044\u3001\u30bf\u30a4\u30df\u30f3\u30b0\u306b\u7e1b\u3089\u308c\u305f\u304f\u306a\u3044<\/span><\/li>\n<\/ul>\n<p>\u30a2\u30d0\u30ca\u30a4\u30c8\u306f\u6700\u77ed15\u5206\u3067\u52b9\u679c\u3092\u767a\u63ee\u3059\u308b\u4ed6\u3001\u300c\u98df\u4e8b\u306e\u5f71\u97ff\u3092\u53d7\u3051\u306b\u304f\u3044\u300d\u3068\u3044\u3046\u7279\u5fb4\u304c\u3042\u308a\u307e\u3059\u3002<br \/>\n\u9ad8\u8102\u8cea\u306e\u30e1\u30cb\u30e5\u30fc\u3092\u907f\u3051\u3001\u8179\u516b\u5206\u76ee\u3067\u6291\u3048\u308b\u3053\u3068\u3055\u3048\u5fc3\u304c\u3051\u308c\u3070\u3001<span class=\"yellow-line\">\u98df\u5f8c\u306e\u670d\u7528\u3067\u3082\u52b9\u679c\u3092\u767a\u63ee\u3057\u307e\u3059\u3002<\/span><br \/>\n\u300c\u98df\u4e8b\u306e\u5f71\u97ff\u3092\u53d7\u3051\u3084\u3059\u3044\u305f\u3081\u7a7a\u8179\u6642\u306e\u670d\u7528\u304c\u57fa\u672c\u300d\u3068\u3055\u308c\u3066\u3044\u308b\u30d0\u30a4\u30a2\u30b0\u30e9\u306b\u6bd4\u3079\u308b\u3068\u3001\u305d\u306e\u70b9\u306f\u4fbf\u5229\u3067\u3042\u308b\u3068\u3044\u3048\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n<p>\u305f\u3060\u3057\u3001\u3042\u304f\u307e\u3067\u3082\u300c\u5f71\u97ff\u3092\u53d7\u3051\u306b\u304f\u3044\u300d\u3068\u3044\u3046\u8a71\u3067\u3042\u3063\u3066\u3001<span class=\"yellow-line\">\u7a7a\u8179\u6642\u306b\u670d\u7528\u3057\u305f\u307b\u3046\u304c\u3088\u308a\u52b9\u679c\u3092\u5b9f\u611f\u3057\u3084\u3059\u3044\u50be\u5411\u306b\u3042\u308b<\/span>\u3053\u3068\u306f\u62bc\u3055\u3048\u3066\u304a\u3044\u305f\u307b\u3046\u304c\u826f\u3044\u3067\u3057\u3087\u3046\u3002<\/p>\n<h2><span id=\"i\">\u52c3\u8d77\u306e\u30ab\u30ae\u3068\u306a\u308b\u306e\u306f\u6027\u7684\u8208\u596e\u3084\u523a\u6fc0<\/span><\/h2>\n<p><img decoding=\"async\" loading=\"lazy\" src=\"\/column\/wp-content\/uploads\/seiteki_koufun.webp\" alt=\"\u6027\u7684\u8208\u596e\" width=\"400\" height=\"300\" class=\"alignleft size-full wp-image-10847\" \/>\u3053\u308c\u306f\u3001\u306a\u304b\u3070\u4f59\u8ac7\u306e\u3088\u3046\u306a\u3082\u306e\u3067\u3059\u304c&hellip;&hellip;\u3002<br \/>\n\u30a2\u30d0\u30ca\u30a4\u30c8\u3084\u30d0\u30a4\u30a2\u30b0\u30e9\u306b\u9650\u3089\u305a\u3001<span 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